Incidence of SARS-CoV-2 infection in close contacs. Telephone follow-up in Primary Care.

OBJECTIVE: To study the incidence of infection in close contacts with patiens with SARS-CoV-2 infection using a telephone monitoring protocol after the recommendation of isolation and quarantine at home. PATIENTS AND METHODS: Cohort study, with 124 patients older than 15 years, included consecutively, asymptomatic at the time of the consultation, who had had close contact (<2 m) with confirmed or possible cases of SARS-CoV-2 infection. The intervention consisted of 2 weeks of home isolation and quarantine, contacting by phone on days, 2, 4, 7 and 14 after the contact. The event of interest was the appereance of symptoms compatible with SARS-CoV-2 infection. RESULTS: The average age was 45.1 years (55.6% women); 328 phone calls were made (average 2.6 calls for patient). After 2 weeks of follow-up, 6 patients developed symptoms, confirming serologically or by PCR in 3 of them (2.4%, CI 95%: 0.8-6.9). CONCLUSIONS: The incidence of SARS-CoV-2 infection in close contacts is low 2 weeks after home isolation and quarantine at home.

OBJETIVO: Estudiar mediante un protocolo de seguimiento telefónico la incidencia de infección en los contactos estrechos de pacientes con infección por SARS-CoV-2 tras la recomendación de aislamiento y cuarentena en el domicilio. PACIENTES Y MÉTODOS: Estudio de cohortes, con 124 pacientes mayores de 15 años, incluidos consecutivamente, asintomáticos en el momento de la visita, con contacto estrecho (<2 metros) con casos confirmados o posibles de infección por SARS-CoV-2. La intervención consistió en aislamiento y cuarentena en domicilio durante 2 semanas, contactando telefónicamente los días 2, 4, 7 y 14 tras el contacto. El evento de interés fue la aparición de clínica compatible con infección por SARS-CoV-2. RESULTADOS: La edad media fue de 45,1 años (55,6% mujeres). Se realizaron 328 llamadas telefónicas (media de 2,6 llamadas por paciente). Tras 2 semanas de seguimiento desarrollaron síntomas 6 pacientes, confirmados serológicamente o por PCR en 3 de ellos (2,4%; IC 95%: 0,8­6,9). CONCLUSIONES: La incidencia de infección por SARS-CoV-2 en los contactos estrechos es baja a las 2 semanas tras el aislamiento y cuarentena domiciliarios.

[Incidence of SARS-CoV-2 infection in close contacs. Telephone follow-up in Primary Care]. / Incidencia de infección por SARS-CoV-2 en contactos estrechos. Seguimiento telefónico en Atención Primaria.

OBJECTIVE: To study the incidence of infection in close contacts with patiens with SARS-CoV-2 infection using a telephone monitoring protocol after the recommendation of isolation and quarantine at home. PATIENTS AND METHODS: Cohort study, with 124 patients older than 15 years, included consecutively, asymptomatic at the time of the consultation, who had had close contact (<2 meters) with confirmed or possible cases of SARS-CoV-2 infection. The intervention consisted of 2 weeks of home isolation and quarantine, contacting by phone on days, 2, 4, 7 and 14 after the contact. The event of interest was the appereance of symptoms compatible with SARS-CoV-2 infection. RESULTS: The average age was 45.1 years (55.6% women); 328 phone calls were made (average 2.6 calls for patient). After 2 weeks of follow-up, 6 patients developed symptoms, confirming serologically or by PCR in 3 of them (2.4%, CI 95%: 0.8-6.9). CONCLUSIONS: The incidence of SARS-CoV-2 infection in close contacts is low 2 weeks after home isolation and quarantine at home.